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Vol. 22, Art. 52 (pp. 728-735) | 2021
Using in vitro methods for predicting toxicity and mechanisms of action of mycotoxins
Federal State Unitary Enterprise «Research Institute of Hygiene, Toxicology and Occupational Pathology» of Medical and Biological Agency
Brief summary
The paper assesses the possibility of predicting the toxicometric parameters of some mycotoxins for humans based on a set of acute toxicity indicators obtained on animals and cytotoxicity values for lymphocyte cultures of laboratory animals and humans. A change in the level of apoptosis of rat and human lymphocytes under the influence of mycotoxins, as well as the effect of substances changing calcium metabolism in cells on this process, was assessed Key words Apoptosis, lymphocytes, mycotoxins, toxicity, cytotoxicity (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
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