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Медико-биологический
информационный портал
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Vol. 19, Art. 19 (pp. 258-268) | 2018
The research of ladasten effect on laboratory animals physical working capacity while performing multiple physical activities in various levels of fatigue under hypobaric anaxia
Kaltygin M.V.1, Begashvili A.N.1, Vetryаkov O.V.2, Fateev I.V.1, Ivchenko E.V.1, Pivovarov M.A.1, Malachova I.S.1
State Scientific-Research Test Institute of Military Medicine of Department of Defense of the Russian Federation The federal state budget military educational institution of higher education Military medical academy n. a. S.M. Kirov.
Brief summary
The effect of ladasten in various dosages on physical working capacity of laboratory animals (white rats) was studied in "swimming with a load" test and "treadmill running" test. It was shown that single endogastric administration of ladasten in 12,5 80 mg/kg leads to an increase of duration of rats swimming ability while performing multiple physical activities. The most positive effect on physical working capacity was observed following ladasten administration in doses 42-58 mg/kg and in doses 42-68 mg/kg under hypobaric anoxia (in "treadmill running" test). Key words ladasten, physical working capacity, swimming with a load test, treadmill, actoprotective action. (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
Reference list 1. Avtorskoe svidetelstvo SSSR N860446 "Zameshennie N-adamantani, proyavlyaushie psihostimyliryushyu aktivnost", Valdman?A.V., Zaiceva?N.M., Klimova?N.V. i dr. Bulleten izobretenii, 1993. - N?43-44. 2. Morozov I.S., Klimova N.V., Sergeeva S.A. i dr. Proizvodnie adamantana, povishaushie ystoichivost organizma k ekstremalnim vozdeistviyam // Vestnik RAMN. - 1999. - N?3. - C.?28-32. 3. Morozov I.S., Petrov V.I., Sergeeva S.A. Farmakologiya adamantanov. - Volgograd, 2001. - 221 s. 4. Morozov I.S., Pyhova G.S,, Avdylov N.A. Mehanizmi neirotropnogo deistviya bromantana // Eksp. klin. farmakol. - 1999. - T.?62, N?1. - S.?11-14. 5. Vasilev P.V. Farmakologiya v aviacionnoi medicine / P.V.?Vasilev, G.D.?Glod, S.I.?Sitnik // Spravochnik aviacionnogo vracha. - M.: Vozdyshnii transport, 1993. - S.?148. 6. Burnat P., Payen A., Le Brumant-Payen C. [et al.]. Bromontan, a new doping agent // Lancet. - 1997. - Vol. 350, N 9082. - p. 963-964. 7. Oliynyk S., Oh S. The pharmacology of actoprotectors: practical application for improvement of mental and physical performance // Biomol. Ther. (Seoul). - 2012. - Vol.?20, N?5. - P.?446-456. 8. Morozov I.S., Kleimenova N.N. Vliyanie bromantana na fizicheskyu rabotosposobnost laboratornih jivotnih // Eksp. i klin. farmakol. - 1998. - T.?61, N?6. - S. 51-53. 9. Cyblova E.G. Izychenie aktoprotektornoi aktivnosti novih geteroaromaticheskih soedinenii / Avtoref. diss. ? kand. biol. nayk. - Kypavna, 2001. - 23?s. 10. Cyblova E.G., Ivanova T.N., Yasnecov V.V. [i dr.]. Sintez i vliyanie na fizicheskyu rabotosposobnost novih proizvodnih 2-amino-6-etoksibenzotiazola // Him.-farm. jyrnal. - 2015. - T.?49, N?10. - S.?30-33. 11. Katynina N.P., Babaniyazova Z.H., Averyanova S.A. [i dr.]. Vliyanie metallokompleksnih proizvodnih?imidazola na fizicheskyu rabotosposobnost mishei po testy plavaniya v basseine // Vestn. MANEB. - 2008. - T.?13, N?2. - S.?187-188. 12. Katynina N.P., Tarasova O.A., Babaniyazova O.A. [i dr.]. Vliyanie metallokompleksnih proizvodnih?imidazola na prodoljitelnost bega mishei v tretbane // Vestn. MANEB. - 2008. - T.?13, N?2. - S.?184-185. 13. Belenkii M.L. Elementi kolichestvennoi ocenki farmakologicheskogo effekta / M.L. Belenkii. - L.: Medgiz, 1963. - 152 s.; 14. Glans?S. Mediko-biologicheskaya statistika / S.?Glans. - M.: "Praktika", 1998. - 459 s. |
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