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Vol. 16, Art. 85 (pp. 963-968) | 2015
Influence apolipoprotein a-i in complex with estrone on dna biosynthesis in rat hepatocyt culture
Trifonova N.V., Knyazev R.A., Polyakov L.M.
"Institute of Biochemistry", Novosibirsk
Brief summary
The paper shows that apolipoprotein AI (apoA-I) forms a complex with a female sex hormone - estrone. Calculated binding constant for complecses apoA-I-hormone. In the culture of rat hepatocytes demonstrated that complex apoA-I-estrone enhances the proliferation of rat hepatocytes against the simple hormone without a carrier. It is assumed that the resulting effect is realized by means of receptor-mediated endocytosis. Key words hepatocytes, lipoproteins, apolipoprotein A-I (apoA-I), estrone, DNA biosynthesis. (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
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