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Vol. 16, Art. 67 (pp. 728-736)    |    2015       

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Вiomarkers of exposure and effect of beryllium

Lukovnikova L.V., Stosman K.I., Krupkin A.B., Ivanova A.S.

«Institute of Toxicology» of Federal Medico-Biological Agency, Federal State Unitary Scientific-research institute of Industrial and Marine Medicine of Federal Medical-Biological Agency

Brief summary

Staff's control, who has professional contact with beryllium, makes clear that most of working personnel revealed violations of balance in cytokine system, as well as increase the level of immunoglobulins E. The obtained results allow to recommend the interactive immunological monitoring of personnel engaged in manufacturу in order to develop comprehensive prevention programmes and diagnostic of professional deseases.


Key words

beryllium, immunological monitoring , biomarkers of exposure and effect

Reference list

1. Vrednie veshestva v okryjaushei srede. Elementi I-IV grypp periodicheskoi sistemi i ih neorganicheskie soedineniya: spravochno – enciklopedicheskoe izdanie // Redaktor-organizator V.A. Filov i dr. – SPb.: NPO «Professional», 2005. – 462 s.


2. Filov V.A. Berillii i ego soedineniya: okryjaushaya sreda, toksikolo-giya, gigiena // Rossiiskii himicheskii jyrnal. – 2004. – T. XLVIII, № 2. – S.76-86.


3. Berylium. EHC 106. Geneva: WHO, 1990. – 210 p.


4. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. V. 58. Lion: IARC, 1993. – p. 41–117.


5. Lykovnikova L.V., Frolova A.D., Chekynova M.P. Metalli v okryjaushei srede: problemi monitoringa // Efferentnaya terapiya. – 2004. – №1. – S.74-79.


6. Lykovnikova L.V., Sidorin G.I. Biomonitoring v sisteme ocenki riska himicheskogo vozdeistviya / Sbornik trydov IV cezda toksikologov Rossii. Moskva. – 2013. – S. 299-301.


7. Frolova A.D., Lykovnikova L.V., Chashin V.P., Sidorin G.I. K probleme monitoringa himicheskih veshestv // Medicina tryda i promishlennaya ekologiya. – 2003. –№8. – S.1–6.


8. TLVs and BEIs, Based on the Documentations for Threshold Limit Values for Chemical Substances and Physical Agents Biological Exposure Indices, ACGIH, WORLDWIDE, 1999. – 184 p.


9. Tryd i zdorove/ N.F. Izmerov, I.V. Byhtiyarov, L.V. Prokopenko, N.I. Izmerova, L.P. Kyzmina – M.:Litterra, 2014. – 416 s.


10. Alekseeva O.G. Allergiya pri vozdeistvii himicheskogo faktora. // Profilakticheskaya toksikologiya. Centr mejdynarodnih proektov GKNT. – Moskva. – 1984. – S.323-332.


11. Alekseeva O.G. Allergiya k promishlennim himicheskim soedineniyam / Alekseeva O.G., Dyeva L.A. – M.: Medicina, 1978. – 278 s.


12. Gazalieva M.A. Immynnie mehanizmi pri vozdeistvii soedinenii berilliya v eksperimente // Gigiena tryda i medicinskaya ekologiya. – 2009. – №4 (25).– S.68 – 69.


13. Haitov R.M., Pinegin B.V., Istamov H.I. Ekologicheskaya immynologiya. – M.: VNIRO, 1995. – 219 s.


14. Sivak K.V., Stosman K.I., Rassoha T.A. i dr. Profilaktika aytosensibilizacii, obyslovlennoi vozdeistviem solei rtyti v eksperimente // Vestnik Sankt-Peterbyrgskoi gosydarstvennoi medicinskoi akademii im. I.B. Mechnikova. – 2008. – № 1. – S.84–87.


15. Krypkin A.B., Kovigin G.F., Bitkolov N.Z. i dr. Mediko-ekologicheskie aspekti zashiti proizvodstvennoi sredi pri polychenii i obrabotke berilliya i izdelii iz nego. – Sankt - Peterbyrg, 2011. – 456 s.


16. Sanockii I.V. Problema otdalennih posledstvii vozdeistviya ekotoksikantov // Medicinskie aspekti radiacionnoi i himicheskoi bezopasnosti. – Sankt - Peterbyrg, 2001. – S.5.


17. Reinhild Klein, Michael Schwenk, Douglas M. Templeton. // Pure Appl. Chem. – 2006. –Vol. 78, №. 11. – P. 2155–2168.


18. Toxicological profile for beryllium. U.S. Department of health and human services Public Health Service Agency for Toxic Substances and Disease Registry. – 2002. – 247 p.


19. Maier L.A., Sawyer R.T., Tinkle L.A. et all. // Eur Respir J.– 2001, №17. – P. 403–415.


20. Drannik G.N. Klinicheskaya immynologiya i allergologiya. – M.: MIA, 2003. – 603 s.


21. Pevnickii L.A. Ekologicheskii immynodeficit: immynogeneticheskie aspekti ego razvitiya i korrekcii // Vestnik RAMN. –1994. – №4. – S.20–27.


22. Smirnov V.S., Petlenko S.V., Sosukin A.E. Sostoyanie immynnoi sistemi pri ostrom i hronicheskom vozdeistvii himicheskih ksenobiotikov // Teoreticheskie i prikladnie problemi klinicheskoi toksikologii. – 1999. – S.85-103.


23. Pol Y.E. Immynologiya. – M.: Mir, 1988. – T.3. – 360 s.


24. Yarilin A.A. Osnovi immynologii. – M.: Medicina, 1999. – 607s.


25. Mosmann T. R., Sad S. // Immunol. Today. – 1996, № 17. – P. 138–146.


26. Romagnani S. // Clin.Immunol.Immunopath. – 1996, № 80. – P. 225–235.


27. Bortkevich L.G., Sykovatih T.N., Sapynova T.A. i dr. Sintez citokinov, indycirovannii specificheskimi allergenami // Citokini i vospalenie. – 2002. – T.1, №2. – S.6.


28. Silkov A.N., Kovalevskaya-Kycheryavenko T.V., Sennikova S.V. Citokini v immynopatogeneze atopicheskogo dermatita // Citokini i vospalenie. – 2012. – T.11, №1.– S. 5-10.

Журнал основан 16 ноября 2000г.
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