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Медико-биологический
информационный портал
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для специалистов |
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Vol. 12, Art. 92 (pp. 1134-1146) | 2011
Cell models for search of substanses promoting reverse cholesterol transport
1- Institute for Atherosclerosis Research: 4-1 I. Franko Str., 121355, Moscow, Russia.
2- Institute of General Pathology and Pathophysiology: 8 Baltiyskaya Str., 125315, Moscow, Russia.
Brief summary
Cultured cell models have been developed to study the cholesterol efflux from the arterial wall as an integral indicator of reverse cholesterol transport. The models and the results of in vivo and ex vivo experiments can be used to propose new antiatherosclerotic drugs and elucidate their mood of action. Key words cholesterol, atherosclerosis, cultured cell models, antiatherosclerotic drugs. (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
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