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Vol. 27, Art. 7 (pp. 140-158)    |    2026       

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The effect of electromagnetic radiation on erythrocyte membrane permeability and the lead acetate content in rat brain and myocardial tissues

Terekhina N.A.1, Terekhin G.A.2, Selin A.D.1, Orbidans A.G.2, Guljaev D.K.2

1Vagner Perm State Medical University, Perm, Russian Federation
2Perm State Pharmaceutical Academy, Perm, Russian Federation

Brief summary

The widespread use of cellular communication creates a novel environmental factor - «electromagnetic smog» - which possesses a broad spectrum of destructive biological activity. Objective. To evaluate the influence of electromagnetic radiation on erythrocyte membrane permeability and the content of lead acetate in rat brain and myocardial tissues. Materials and Methods. The control group was not exposed to the factors under study. The comparison group received a single intragastric dose of lead acetate solution (1,0 mg/kg). The animals in the experimental group were intragastrically administered a single dose of an aqueous lead acetate solution (1,0 mg/kg) after a 60-day exposure to the electromagnetic field (EMF) and were then subjected to further EMF exposure for an additional 30 days. Results. Increased permeability of erythrocyte membranes was observed both after 3 months of prolonged EMR exposure in an in vivo model and after a short-term 90-minute exposure in an in vitro model. The lead content in the brain and myocardial tissues of rats subjected to combined exposure to decimeter-range EMR and lead acetate poisoning was 3,5 times higher than in the comparison group, which received lead acetate without EMR exposure. Conclusion. Electromagnetic radiation increases the permeability of erythrocyte membranes in rat peripheral blood, leading to elevated lead acetate levels in brain and myocardial tissues.


Key words

electromagnetic radiation; erythrocyte membrane permeability; lead; brain; myocardium

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