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Федеральное государственное бюджетное учреждение науки
Институт теоретической и экспериментальной биофизики
Российской академии наук


ООО "ИЦ КОМКОН"

ФГБУН "Институт токсикологии" ФМБА России

Адрес редакции и реквизиты

192012, Санкт-Петербург, ул.Бабушкина, д.82 к.2, литера А, кв.378

Свидетельство о регистрации электронного периодического издания ЭЛ № ФС 77-37726 от 13.10.2009
Выдано - Роскомнадзор

ISSN 1999-6314


Фундаментальные исследования • Патологическая анатомия

Том: 21
Статья: « 79 »
Страницы:. 1005-1024
Опубликована в журнале: 10 сентября 2020 г.
English version

Методы визуализации глиобластомы. мифы и реальность

Гальковский Б.Э., Митрофанова Л.Б., Рыжкова Д.В., Митрофанов Н.А., Гуляев Д.А.

ФГБУ «НМИЦ им. В.А.Алмазова», Санкт-Петербург, Россия
Первый Санкт-Петербургский государственный медицинский университет им. И.П. Павлова, Санкт-Петербург, Россия


Резюме
Глиобластома - опухоль центральной нервной системы из подгруппы глиом, относиться к 4 степени злокачественности по классификации ВОЗ. Несмотря на огромное количество научных исследований за последние 20 лет, не удалось добиться значительного увеличения продолжительности жизни пациентов после постановки диагноза. Одним из компонентов комплексного лечения глиобластомы является еe хирургическая резекция. Однако, из-за обширного инфильтративного роста даже опытные нейрохирурги не могут четко визуализировать границу между опухолью и здоровой тканью. Кроме того, за кадром остается вопрос об удалении зоны перифокального роста глиобластомы, которая является источником еe рецедива. Обзор составлен в целях систематизации имеющихся в российской и англоязычной литературе данных о методах до-и интраоперационной морфологической визуализации глиобластомы и зоны еe перифокального роста.


Ключевые слова
глиобластома, перифокальная зона, позитронно-эмиссионная томография, магнитно-резонансная томография, нейронавигация с 5-аминолевулиновой кислотой


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