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Медико-биологический
информационный портал
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для специалистов |
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Vol. 16, Art. 83 (pp. 939-947) | 2015
Development of self-emulsifying systems for oral delivery of insulin
V.A.Maltseva, D.I.Efimova, E.A.Rudko, A.K.Nazarov, E.A.Afonkina, A.N.Semenov
FGUP "Scientific Center "Signal", Moscow, ul. Bolshaya Olenya, 8
Brief summary
Self-emulsifying systems were obtained, data of its physicochemical properties were presented and potential of its application for oral delivery of insulin were considered. Resistance of insulin self-emulsifying systems for gastric fluid degradation in vitro was studied and bioavailability of insulin in its systems in vivo was researched. Key words nanoemulsion, self-emulsifying drug delivery systems, oral delivery, bioavailability, insulin. (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
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