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Медико-биологический
информационный портал
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Vol. 12, Art. 90 (pp. 1119-1126) | 2011
The experimental substantiation of the emergency exposure limits of sarin for the air of the working place
Kuznetsova E.A.*, Zhukov V.E., Kolodii T.I.
Research Institute of Hygiene, Toxicology and Occupational Pathology of Federal Medical and Biological Agency of Russia
Brief summary
To substantiate emergency exposure limits of sarin the toxicological parameters of substance: median lethal concentration (CL50), threshold of specific toxic effect (Limac.sp.), threshold of general toxic effect (Limac.integr.) were defined in the experiment with the exposures that lasted for 30 minutes, 1, 2, 4 hours. The dependence “concentration – time - effect” was revealed as the result of the inhalation of sarin. The data were used for the development of the emergency exposure limits of sarin in the air of the working place and the mathematical forecasting of the mentioned limits in the interval from 18 minutes to 5 hours. Key words Sarin, emergency exposure limits, working place, inhalation. (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
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