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Vol. 12, Art. 30 (pp. 353-363)    |    apr 2011       

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Purine analgesia during surgery: adverse effects and complications

Karelov A.E., Semenov D.A., Patlay I.V., Fedorova T.N.

Saint-Petersburg Medical Academy of Postgraduate Studies
Sokolov Clinical Hospital #122 FMBA Russia

Brief summary

Opportunity of purine analgesia using during surgery under general anaesthsia was investigated since the start of 90th of the last century. The goal current study was quality and quantity analysis of adverse effects of intraoperative sodium adenosine thiphosphate infusion. Such effects were observed in 18.3% of patients. Medicine infusion was stopped in several from them because of bradycardia or significant decrease of hemoglobin saturation level.


Key words

purine analgesia, sodium adenosine thiphosphate, adverse effects

Reference list

1. Semenov D.A., Karelov A.E. Analiz dinamiki satyracii gemoglobina kislorodom pri obezbolivanii neselektivnimi agonistami pyrinovih receptorov laparoskopicheskoi holecistektomii // Efferentnaya terapiya. – 2009. – T.15, № 3-4. – S. 107-111.


2. Apan A., Ozcan S., Buyukkocak U. et al. Perioperative intravenous adenosine infusion to extend postoperative analgesia in brachial plexus block // Eur. J. Anaesthesiol. – 2003. – Vol. 20, № 11. – P. 916-919.


3. Benumof G., Fukunada A., Tronsdala F. ATP inhibits hypoxic pulmonary vasoconstriction // Anesthesiology. – 1982. – Vol. 57, №3. – P. 349-358.


4. Forget P., Pirson E., Scholtès J.L. Anaphylactic bronchospasm due to propofol // Anaesth. Intensive Care. – 2009. – Vol. 37, № 5. – P. 865.


5. Möser G.H., Schrader J., Deussen A. Turnover of adenosine in plasma of human and dog blood // Am. J. Physiol. – 1989. – Vol. 256. – P. C799-806.


6. Polosa R., Rorke S., Holgate S.T. Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease // Thorax. – 2002. – Vol. 57. – P. 645-649.


7. Salter M.W., Sollevi A. Roles of purines in nociception and pain // In: M.P. Abbracchio and M. Williams (Editors). – Handbook of experimental pharmacology – Vol. 151/I, Purinergic and pyrimidinergic signalling I molecular, nervous and urogenitary system function. – 2001. – P. 391- 427.


8. Segerdahl M., Ekblom A., Sandelin K. et al. Perioperative adenosine infusion reduces the requirements for isoflurane and postoperative analgesics // Anesth. Analg. – 1995. – Vol. 80. – P. 1145-1149.


9. Segerdahl M., Irestedt L., Sollevi A. Antinociceptive effect of perioperative adenosine infusion in hysterectomy // Acta Anaesth. Scand. – 1997. – Vol. 41. – P. 473-479.


10. Segerdahl M., Persson E., Ekblom A., Sollevi A. Perioperative adenosine infusion reduces the requirements for isoflurane during general anesthesia for shoulder surgery // Acta Anaesth. Scand. – 1996. – Vol. 40. – P. 192-197.


11. Shukla A. Intraoperative bronchospasm with thiopental // Indian J. Anaesth. – 2010. – Vol. 54, № 2. – P. 181-182.


12. Sollevi A. Cardiovascular effects of adenosine in man; possible clinical implications // Prog. Neurobiol. – 1986. – Vol. 27. – P. 319-339.


13. Walsh R.C., Felice K.L., Meehan T.J. Adenosine-induced cardiopulmonary arrest in a patient with paroxysmal supraventricular tachycardia // Am. J. Emerg. Med. – 2009. – Vol. 27, № 7. – P. 901.e1-2.


14. Zarate E., Sa Rego M. M., White P. F. et al. Comparison of adenosine and remifentanil infusions as adjuvants to desflurane anesthesia // Anesthesiology. – 1999. – Vol. 90, № 4. – P. 956-963

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