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Vol. 21, Art. 92 (pp. 1187-1195)    |    2020       

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Lung cancer detection using direct analysis of exhaled breath with semiconductor electronic gas sensors of electronic nose

1N.N. Petrov NMRC of Oncology, Saint-petersburg, Russia
2St. Petersburg Research Institute of Phthisiopulmonology, Saint-Petersburg, Russia

Brief summary

Introduction: The possibility of using non-invasive methods of lung cancer diagnosis by direct analysis of exhaled air. Aim: The study aimed to evaluate the performance of exhaled breath analysis with non-selective methods using cross-sensitivity metal oxide chemiresistor gas sensors in early-stage lung cancer non-invasive detection. Materials and methods: The method was applied in 204 individuals. The conductivity of the sensor is following the concentration of the volatile organic compounds of exhaled breath. The resulting impulse is displayed as a peak on the graph and the area under curve is used as a value of the test. Results: The sensitivity, specificity and accuracy of the analysis of exhaled breath was 91.2%, 100% and 93.4%, respectively. Real-time measurements provide perspectives to use the method for early diagnostics.


Key words

screening, lung cancer, gas analysis, exhaled breath

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