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 УЧРЕДИТЕЛИ:
Федеральное государственное бюджетное учреждение науки
"Институт токсикологии Федерального медико-биологического агентства"
(ФГБУН ИТ ФМБА России)

Институт теоретической и экспериментальной биофизики Российской академии наук.

ООО "ИЦ КОМКОН".




Адрес редакции и реквизиты

199406, Санкт-Петербург, ул.Гаванская, д. 49, корп.2

ISSN 1999-6314

Российская поисковая система
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«
Vol. 14, Art. 11 (pp. 135-147)    |    2013       
»

The therapeutic angiogenesis in the treatment of the chronic ischemic diseases of low extremities
Kargin V.D., Bessmeltsev S.S., Soldatenkov V.E., Burakov V.V., Voloshin S.V., Glazanova T.V., Chebukina Zh.V.

FGBU "Russian Research Institute of Hematology and Blood Transfusion of the Federal Medical and Biological Agency"



Brief summary

Certain limit has been achieved in the treatment of progressive ischemic diseases of low extremities by means of surgical revascularization and medical drug treatment. Diseases of peripheral arteries are associated with invalidity of hard-working population that is why the search for the alternative technologies of treatment is very actual. The therapeutic angiogenesis by means of stimulation of natural processes of neovascularisation is one of the new and perspective directions in the treatment of the diseases of peripheral arteries. This article presents the results of experimental studies as well as clinical implementation of cell therapy with the use of autologous transplantation of endothelial cell precursors.


Key words

diseases of peripheral arteries, chronic ischemia of low extremities, neoangiogenesis, hematopoietic stem cells, bone marrow, growth endothelial factors, colony-stimulating factors, apherhesis.





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