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Vol. 12, Art. 46 (pp. 546-557)    |    2011       

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The golgi apparatus and glycosaminoglycan

Lukashin B.P., Grebenyuk A.N.

Military Medical Academy named S.M. Kirov

Brief summary

Heparin is a highly acidic polysaccharide and a member of a family of biopolimers called glycosaminoglycan. The structure and activities of glycosaminoglycans are detailed along with recent advances in glycosaminoglycan structural analysis and biological evaluation. The Golgy apparatus can be consiered as a cellular headquarters where basic metabolism, signalling and cell fate decisional processes converse.


Key words

the apparatus Golgi, glycosaminoglycans, oligosaccharides, heparin, heparan sulfate, chemoenzymatic synthess, glycosylation, signalling pathways.

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