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Информационное партнерство

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Vol. 9, Art. 16 (pp. 149-159)    |    2008       

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Brief summary

A new approach to determination of the composition of mixed lipid-detergent aggregates and the concentration of detergent in aqueous phase was developed for the systems containing detergent of high critical micelle concentration. The method requires only a small number of lipid-detergent mixtures (minimum 4) for measurements and enables estimating the measured parameters as a function of temperature and phase state of lipid. This method was used for the study of the dimyristoylphosphatidylcholine-sodium cholate system.


Key words

detergent/lipid ratio in mixed aggregates, aqueous detergent concentration, lipid-detergent systems, DSC, phase transitions.

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