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VOL. 8, ART. 46 (pp. 497-517) // september 2007 y.

A succinate-based composition "rejuvenates" aging mice and alleviates menopausal symptoms in women without sex hormone replacement therapy

Eugene I. Maevsky, Andrey B. Peskov, Mikhail L. Uchitel, Alexander G. Pogorelov, Natalia Yu. Saharova, Elene F. Vihlyantseva, L.A.Bogdanova, Marie N. Kondrashova
Institute of Theoretical and Experimental Biophysics RAS, ul.,Institutskaya, 3, Pushchino , Moscow region, 142290, Russia
Institute of Medicine, Ecology and Sport, Ulyanovsk State University, ul. Karla Libkhnehta, 1, Ulyanovsk, 432970, Russia,

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Abstract:

Menopausal transition is often accompanied by a variety of adverse pathological symptoms, currently treated with hormone replacement therapy, which is associated with a number of health risks. This report investigated the role of a food supplement-a composition of energy-exchange metabolites, with succinate as the main component-for treating menopausal syndrome.

Key words: menopause, aging, food supplement, succinate, estradiol

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