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Vol. 23, Art. 46 (pp. 767-779)    |    2022       

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The influence of alternating magnetic field of extremely low frequency on postnatal development of rats

S.I. Alekperov, A.A. Suetov, V.I. Efremov, A.N. Kimstach, A.V. Kolunov, I.M. Karpin, A.N. Sazhnev

Federal State Budgetary Esteblishment « State scientific research test Institute of the military medicine of the Russian Federation Defense Ministry»

Brief summary

Purpose. To investigate the effects of prolonged exposure to an alternating magnetic field (AMF) 8 Hz at different levels of magnetic field intensity on the postnatal development of rats. Materials and methods. Thirty pregnant female rats (age 10 weeks) included in 3 equal groups according to the intensity of magnetic field (4 kA/m, 6,5 kA/m and sham control) were exposed to AMF 2 h/day from the moment of mating and continued exposure to the offspring until the total exposure time of 10 weeks. Physical development, formation of sensory-motor reflexes, emotional-motor behavior and ability to fine coordination of movements, locomotor activity on the 20th and 45th days of life during testing in the "open field" were evaluated in the obtained offspring. Results. Under the AMF 8 Hz 6,5 kA/m exposure the number of pups in rat litters was significantly less than rats in comparison with control (p=0.03). The average weight of the pups in the litters in both experimental groups in the first week of life was significantly higher (p<0,05), further differences in weight of females and males in comparison with the control was not detected. In the physical development and formation of sensory-motor reflexes, delay in some parameters was noted (p<0,05), but no dose-dependent effects of AMF exposure were revealed. When tested in the "open field" on the 20th day revealed the presence of stress and anxiety of animals of experimental groups, with further testing on the 45th day, the behavior of animals in experimental groups did not differ from the control group. Conclusion. The exposure of AMF 8 Hz on rats during embryonic and postnatal development does not lead to deviations in physical and sensory motor development, and has no pronounced influence on the behavior of rats who have reached adult age.


Key words

alternating magnetic field, postnatal development, electromagnetic radiation, chronic exposure, reflexes

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