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Vol. 21, Art. 84 (pp. 1074-1088)    |    2020       

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Telocytes in the human heart and brain in health and disease

Almazov National Medical Research Centre, St. Petersburg, 197143
A.A. Smorodintsev Research Institute of Influenza, St. Petersburg, 197376

Brief summary

The literature review highlights the structure and immunophenotype of heart and brain telocytes, features of the distribution of these cells in various parts of the heart and central nervous system, describes the change in the density of interstitial pacemakers in myocardial infarction, ventricular fibrillation, chronic heart failure, as well as an increase in their number in the vessels of glioblastoma. The review discusses the role of telocytes in the carcinogenesis of malignant glioma.


Key words

telocytes, heart, brain, glioblastoma

Reference list

1.Popescu L. M., Ciontea S. M., Cretoiu D. Interstitial Cajal‐like cells in human uterus and fallopian tube //Annals of the New York Academy of Sciences. - 2007. - Vol. 1101. - ?. 1. - P. 139-165.


2. Popescu L. M., Faussone‐Pellegrini M. S. TELOCYTES-a case of serendipity: the winding way from Interstitial Cells of Cajal (ICC), via Interstitial Cajal‐Like Cells (ICLC) to TELOCYTES //Journal of cellular and molecular medicine. - 2010. - Vol. 14. - ?. 4. - P. 729-740.


3. Zheng Y., Bai C., Wang X. Telocyte morphologies and potential roles in diseases //Journal of cellular physiology. - 2012. - T. 227. - ?. 6. - S. 2311-2317.


4. Pellegrini M. S. F., Popescu L. M. Telocytes //BioMolecular concepts. - 2011. - Vol. 2. - ?. 6. - P. 481-489.


5. Gherghiceanu M., Popescu L. M. Heterocellular communication in the heart: electron tomography of telocyte-myocyte junctions //Journal of cellular and molecular medicine. - 2011. - Vol. 15. - ?. 4. - P. 1005-1011.


6. Mandache E., Popescu L. M., Gherghiceanu M. Myocardial interstitial Cajal‐like cells (ICLC) and their nanostructural relationships with intercalated discs: shed vesicles as intermediates //Journal of Cellular and Molecular Medicine. - 2007. - Vol. 11. - ?. 5. - P. 1175-1184.


7. Hinescu M. E., Popescu L. M. Interstitial Cajal‐like cells (ICLC) in human atrial myocardium //Journal of cellular and molecular medicine. - 2005. - Vol. 9. - ?. 4. - P. 972-975.


8. Hinescu M. E. et al. Interstitial Cajal‐like cells (ICLC) in atrial myocardium: ultrastructural and immunohistochemical characterization //Journal of cellular and molecular medicine. - 2006. - Vol. 10. - ?. 1. - P. 243-257.


9. Liu J. et al. Symbol. Distribution of Telocytes in the rat heart //Journal of Clinical Rehabilitative Tissue Engineering Research. - 2011. - Vol. 15. - ?. 19. - P. 3546-3548.


10. Kostin S. Cardiac telocytes in normal and diseased hearts //Seminars in cell & developmental biology. - Academic Press, 2016. - Vol. 55. - P. 22-30.


11. Mitrofanova L. B. i dr. Telociti v sino-atrialnom yzle cheloveka. Morfologicheskoe dokazatelstvo peismekernoi aktivnosti kletok i vozmojnosti provodit elektricheskii impyls //Rossiiskii kardiologicheskii jyrnal. - 2017. - T. 9 - ?149. - S. 42-49.


12. Mitrofanova L. B. et al. Telocytes in the human sinoatrial node //Journal of cellular and molecular medicine. - 2018. - Vol. 22. - ?. 1. - P. 521-532.


13. Cretoiu D. et al. Human cardiac telocytes: 3D imaging by FIB‐SEM tomography //Journal of cellular and molecular medicine. - 2014. - Vol. 18. - ?. 11. - P. 2157-2164.


14. Gherghiceanu M., Popescu L. M. Cardiomyocyte precursors and telocytes in epicardial stem cell niche: electron microscope images //Journal of cellular and molecular medicine. - 2010. - Vol. 14. - ?. 4. - P. 871-877.


15. Kostin S., Popescu L. M. A distinct type of cell in myocardium: interstitial Cajal‐like cells (ICLCs) //Journal of cellular and molecular medicine. - 2009. - Vol. 13. - ?. 2. - P. 295-308.


16. Popescu L. M. et al. Insights into the interstitium of ventricular myocardium: interstitial Cajal‐like cells (ICLC) //Journal of cellular and molecular medicine. - 2006. - Vol. 10. - ?. 2. - P. 429-458.


17. Iancu C. B. et al. Myocardial telocyte-like cells: A review including new evidence //Cells Tissues Organs. - 2018. - Vol. 206. - ?. 1-2. - P. 16-25.


18. Mandache E. et al. Telocytes in human isolated atrial amyloidosis: ultrastructural remodelling //Journal of cellular and molecular medicine. - 2010. - Vol. 14. - ?. 12. - P. 2739-2747.


19. Zhao B. et al. Cardiac telocytes were decreased during myocardial infarction and their therapeutic effects for ischaemic heart in rat //Journal of cellular and molecular medicine. - 2013. - Vol. 17. - ?. 1. - P. 123-133.


20. Manole C. G. et al. Experimental acute myocardial infarction: telocytes involvement in neo‐angiogenesis //Journal of cellular and molecular medicine. - 2011. - Vol. 15. - ?. 11. - P. 2284-2296.


21. Cismasiu V. B., Popescu L. M. Telocytes transfer extracellular vesicles loaded with micro RNA s to stem cells //Journal of cellular and molecular medicine. - 2015. - Vol. 19. - ?. 2. - P. 351-358.


22. Suciu L., Nicolescu M. I., Popescu L. M. Cardiac telocytes: serial dynamic images in cell culture //Journal of cellular and molecular medicine. - 2010. - Vol. 14. - ?. 11. - P. 2687-2692.


23. Ja K. P. M. M. et al. iPSC‐derived human cardiac progenitor cells improve ventricular remodelling via angiogenesis and interstitial networking of infarcted myocardium //Journal of cellular and molecular medicine. - 2016. - Vol. 20. - ?. 2. - P. 323-332.


24. Galrinho RD, Manole CG, Vinereanu D.Telocytes-a Hope for Cardiac Repair after Myocardial Infarction //Maedica. - 2016. - Vol. 11. - ?. 4. - P. 325-329.


25. Manetti M. et al. A loss of telocytes accompanies fibrosis of multiple organs in systemic sclerosis //Journal of cellular and molecular medicine. - 2014. - Vol. 18. - ?. 2. - P. 253-262.


26. Mitrofanova L. B. i dr. Morfologicheskoe issledovanie telocitov v levom predserdii y pacientov s dlitelno persistiryushei fibrillyaciei predserdii //Rossiiskii kardiologicheskii jyrnal. - 2019. - ?. 7. - S. 53-62.


27. Richter M., Kostin S. The failing human heart is characterized by decreased numbers of telocytes as result of apoptosis and altered extracellular matrix composition //Journal of cellular and molecular medicine. - 2015. - Vol. 19. - ?. 11. - P. 2597-2606.


28. Gawad S. K. M. A. et al. Histological and immunohistochemical study of telocytes in the heart of male albino rats in different age groups //The Scientific Journal of Al-Azhar Medical Faculty, Girls. - 2020. - Vol. 4. - ?. 3. - P. 373-382.


29. Popescu B. O. et al. Telocytes in meninges and choroid plexus //Neuroscience letters. - 2012. - Vol. 516. - ?. 2. - P. 265-269.


30. Mitrofanova L. B. i dr. Morfologicheskoe issledovanie telocitov v razlichnih otdelah normalnogo golovnogo mozga vzroslogo cheloveka //Medline. ru. Rossiiskii biomedicinskii jyrnal. - 2018. - T. 19. - ?. 1. - S. 281-306.


31. Pataskar A. et al. NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program //The EMBO journal. - 2016. - Vol. 35. - ?. 1. - P. 24-45.


32. Ozdemir-Kaynak E., Qutub A. A., Yesil-Celiktas O. Advances in glioblastoma multiforme treatment: new models for nanoparticle therapy //Frontiers in physiology. - 2018. - Vol. 9. - P. 170.


33. Mitrofanova L. et al. Morphological and immunophenotypic characterization of perivascular interstitial cells in human glioma: Telocytes, pericytes, and mixed immunophenotypes //Oncotarget. - 2020. - Vol. 11. - ?. 4. - P. 322-346.


34. Hirota S. et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors //Science. - 1998. - Vol. 279. - ?. 5350. - P. 577-580.


35. Heinrich M. C. et al. PDGFRA activating mutations in gastrointestinal stromal tumors //Science. - 2003. - Vol. 299. - ?. 5607. - P. 708-710.


36. Frolov A. et al. Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling //Scientific reports. - 2016. - Vol. 6. - ?. 1. - P. 1-12.


37. De Witt Hamer P. C. Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies //Neuro-oncology. - 2010. - Vol. 12. - ?. 3. - P. 304-316.


38. Wen P. Y. et al. Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08 //Clinical Cancer Research. - 2006. - Vol. 12. - ?. 16. - P. 4899-4907.


39. Soni V. S., Yanagihara T. K. Tumor treating fields in the management of Glioblastoma: opportunities for advanced imaging //Cancer Imaging. - 2019. - Vol. 19. - ?. 1. - P. 76.


40. Kirson E. D. et al. Disruption of cancer cell replication by alternating electric fields //Cancer research. - 2004. - Vol. 64. - ?. 9. - P. 3288-3295.


41. Kirson E. D. et al. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors //Proceedings of the National Academy of Sciences. - 2007. - Vol. 104. - ?. 24. - P. 10152-10157.


42. Rehman A. A., Elmore K. B., Mattei T. A. The effects of alternating electric fields in glioblastoma: current evidence on therapeutic mechanisms and clinical outcomes //Neurosurgical focus. - 2015. - Vol. 38. - ?. 3. - P. E14.


43. Topfer L. A., Farrah K. Alternating electric fields (?tumour-treating fields?) for the treatment of glioblastoma //CADTH Issues in Emerging Health Technologies. - Canadian Agency for Drugs and Technologies in Health, 2018. P.165.


44. Salvador E, Kessler A, Hoermann J, Domroese D, Schaeffer C. et al. Tumor treating fields effects on the blood-brain barrier in vitro and in vivo. //Journal of Clinical Oncology ? 2020. - Vol. 38. - ?.15suppl. - P. 2551.