1 Federal State Budgetary Institution of Science Institute of Toxicology of the Federal Medical and Biological Agency
2 Federal State Unitary Enterprise Moscow Endocrine Plant
3 Federal State Budget Scientific Institution Scientific Research Institute of Occupational Health. Academician N.F. Izmerov
4 Federal State Autonomous Educational Institution of Higher Education St. Petersburg National Research University of Information Technologies, Mechanics and Optics
The reproductive toxicity of the medication "Morphine hydrochloride, tablet, film-coated, 5 mg and 10 mg" was investigated in experiments on different ontogenesis periods white rats females. The test medication embryotoxic and fetotoxic effects were revealed, the malfunction of fertility and gestation in female rats, the most manifested in animals treated with the drug, starting from the prepubertal period of ontogenesis.