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Vol. 18, Art. 17 (pp. 247-258)    |    2017       

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Assessment of Ultrix? influenza vaccine preventive efficacy in the staff of a large industrial enterprise

Vasilyuk V.B.1, Tyurina A.A.1, Faraponova M.V.1, Zakharov K.A.1,
Verveda A.B.1, Glazkova A.A.2, Polezhaeva N.А.3

1Limited Liability Company Research Center Eco-Safety, 196143, St. Petersburg, Yuriy Gagarin Avenue, 65, Tel. (812) 325-03-05, e-mail: nic@ecosafety.ru
2Limited Liability Company FORT, 127254, Moscow, Dobrolyubova Street, 3, p. 1, of. 103
3Federal budgetary institution of science Moscow Scientific Research Institute of Epidemiology and Microbiology named after GN Gabrichevsky, 125212, Moscow, Admiral Makarov Street,

Brief summary

The study was presented as an analysis of the prophylactic efficacy of a single application of Ultrix? in a dose of 0.5 ml in the case-control type among people employed at a large industrial enterprise in St. Petersburg with a staff of 2,445 people. It was found that the number of patients with ARVI in the main group (employees who received Ultrix?) was 84.7 per 1000 people and was statistically significantly lower (p = 0.0008) than among the unvaccinated subjects - 206.3 per 1000 people. It was shown that the risk of contracting ARVI and influenza in vaccinated people was 2.8 times less than in those who did not receive vaccine prophylaxis. An analysis of the pharmacoeconomic parameters of the enterprise showed that the losses before the Ultrix? vaccine amounted to 8596.1 thousand rubles, wherein the financial loss after the use of the UltriX? vaccine amounted to 5587.5 thousand rubles. The results of the studies testify to the high prophylactic efficacy of Ultrix? influenza vaccine in personnel exposed to harmful and dangerous factors of the production environment. Pharmacoeconomic analysis made it possible to justify the economic feasibility of the use of Ultrix? as a means of nonspecific prevention of ARVI morbidity in large industrial enterprises.


Key words

influenza vaccine, efficacy, personnel, industrial enterprise, harmful and dangerous factors.

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