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Vol. 16, Art. 33 (pp. 350-356)    |    2015       

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Metal-affinity chromatography as a method specificity extraction of harmful chemicals and their derivatives from environmental objects and biological solution

Shreyner E.V., Gladilovich V.D., Keltcieva O.A., Kolonitskyi P.D., Efremov T.A.,
Strukov M.K., Alexandrova M.L., Selutin A.A., Suhodolov N.G., Podolskya E.P.

Federal State Institution of Science "Institute of Toxicology, Federal Medical-Biological Agency"
Institute for Analytical Instrumentation RAS
St. Petersburg State University

Brief summary

The work is devoted to research the possibility of using metal-affinity chromatography for specific extraction of glyphosate, aminomethylphosphonic acid, pirimicarb, fenazepama from aqueous solutions and blood plasma of rats. In work we have used the previously developed two types of metal-affinity sorbents based on Langmuir-Blodgett films and nanosized oxide containing ions of Fe (III), Cu (II), Ni (II). It is shown that this method allows efficient sample preparation in quantitative analysis of water-soluble toxic substances with active functional groups.


Key words

metal-affinity hrogmatografiya, Langmuir-Blodgett films, nanosized oxide, toxic substances.

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