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"Институт токсикологии Федерального медико-биологического агентства"
(ФГБУН ИТ ФМБА России)

Институт теоретической и экспериментальной биофизики Российской академии наук.

ООО "ИЦ КОМКОН".




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199406, Санкт-Петербург, ул.Гаванская, д. 49, корп.2

ISSN 1999-6314

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«
Vol. 16, Art. 105 (pp. 1195-1221)    |    2015       
»

The basic mechanisms of acute thromboembolism of lower limb ischemia
Soroka V.V., Nohrin S.P., Magamedov I.D., Ryazanov A.N.
Department of vascular surgery, Djanelidze Research Institute of Emergency Medicine



Brief summary

Prevention and treatment of acute ischemia is one of the most actual problems of vascular surgery. Attempts of solving these problems with surgery have been taking place since the end of 19-th century. Restoration of arterial blood flow is well studied nowadays. The technique of reconstructive procedures on different region arteries is created, but there is relatively high quantity of complications and death during postoperative period. Primarily, this is so, because local lesions start systemic reactions. "Local" method of regional blood flow lesion treatment hadn't solved the problem of early and late complications in postoperative period. Further studying of ischemia processes and reperfusion syndrome will help improve treatment results. Studying the components of this problem, its' role in the complication development have not only theoretical but clinical meaning for developing prognostic and treatment programs.


Key words

thrombosis, ischemia, reperfusion, inflammation, microcirculation.





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