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Vol. 15, Art. 13 (pp. 134-141)    |    2014       

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Hemodynamic and possible options in the intensive therapy of acute chemical injury verapamil

Yatsinyuk B.B., Sencov V.G.

Brief summary

Evaluation of hemodynamic disorders in acute chemical injury verapamil revealed dominant its influence on myocardial contractility. The response of the cardiovascular system to conduct calcium chloride (0,1-0,2 mg/kg) exhibits increased of the stroke index , volume rate of discharge, power of left ventricular myocardium , suggesting an improvement in the pumping function of the heart and reduce the appearance of inactivity infarction. Bolus of atropine (0,02 mg/kg) resulted in improved contractile ability and increase heart rate. Introduction of dopamine (12-15 ug/kg/min) and noradrenaline (0,02-0,05 mg/kg/min) significantly improved hemodynamic status and glucagon (5,3 mg) has the positive inotropic effect was less pronounced than in dopamine and norepinephrine , but superior performance after administration of atropine. The administered dose of glucagon effect on the frequency of contractions and the diastolic blood pressure was a tendency to increase. Related options therapy show pathogenetic importance analyzed drugs in acute poisoning with verapamil .


Key words

etiology of chemical poisoning, verapamil, hemodynamic instability, correction

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