Prognostic factors and early diagnosis of postoperative infectious complications in colorectal cancer patients
Belyaev A.M., Belousov T.A., Raskin, G.A., Galunova T.J.
Institute of Oncology N.N. Petrov
Brief summary
In the article there are data of microbiological monitoring, immunocytochemical determination of toll-like receptors peritoneal exudate in the postoperative period in patients with colorectal cancer. The article shows the expediency of the microbiological studies peritoneal exudate and definitions toll-like receptors for prediction of infectious complications after surgery in patients with colorectal cancer.
1. Akira S., Takeda K. Toll-like receptor signaling //Nat. Rev. Immunol. – 2004. – V. 4. - P. 499-511.
2. Beutler V. Inferences, questions and possibilities in Toll-like receptor signaling // Nature. - 2004. – V. 430. – P. 257-263.
3. Halliman M., Ramet M., Ezekowitz R.A. Toll-like receptors as Sensors of Pathogen // Pediatric Research. - 2001. - V. 50(3). - P 315-321.
4. Ono S, Tsujimoto H, Hiraki S. et al. Preoperative Toll-like receptor expression in monocytes is associated with host immunological responses following gastrointestinal surgery. // World J Surg. – 2011. – V. 35(2). – P. 365-371.
5. Paun B.C., Cassie S. et al. Risk factors for postoperative complications following rectal cancer surgery. // Ann.Surgery. – 2010. – V. 251(5). – P. 807-818.