Медико-биологический
информационный портал
для специалистов
 
Medline.ru

СОДЕРЖАНИЕ ЖУРНАЛА:
Физико-химическая биология

Клиническая медицина

Профилактическая медицина

Медико-биологические науки


АРХИВ:

Фундаментальные исследования

Организация здравохраниения

История медицины и биологии



Последние публикации

Поиск публикаций

Articles

Архив :  2000 г.  2001 г.  2002 г. 
               2003 г.  2004 г.  2005 г. 
               2006 г.  2007 г.  2008 г. 
               2009 г.  2010 г.  2011 г. 
               2012 г.  2013 г.  2014 г. 
               2015 г.  2016 г.  2017 г. 
               2018 г.  2019 г.  2020 г.  2021 г.  2022 г.  2023 г. 

Редакционная информация:
        Опубликовать статью
        Наша статистика


 РЕДАКЦИЯ:
Главный редактор

Заместители главного редактора

Члены редколлегии
Специализированные редколлегии


 УЧРЕДИТЕЛИ:
Институт теоретической и экспериментальной биофизики Российской академии наук.

ООО "ИЦ КОМКОН".




Адрес редакции и реквизиты

199406, Санкт-Петербург, ул.Гаванская, д. 49, корп.2

ISSN 1999-6314

Российская поисковая система
Искать: 


«
Vol. 12, Art. 92 (pp. 1134-1146)    |    2011       
»

Cell models for search of substanses promoting reverse cholesterol transport
1- Institute for Atherosclerosis Research: 4-1 I. Franko Str., 121355, Moscow, Russia.

2- Institute of General Pathology and Pathophysiology: 8 Baltiyskaya Str., 125315, Moscow, Russia.



Brief summary

Cultured cell models have been developed to study the cholesterol efflux from the arterial wall as an integral indicator of reverse cholesterol transport. The models and the results of in vivo and ex vivo experiments can be used to propose new antiatherosclerotic drugs and elucidate their mood of action.


Key words

cholesterol, atherosclerosis, cultured cell models, antiatherosclerotic drugs.





(The article in PDF format. For preview need Adobe Acrobat Reader)



Open article in new window

Reference list

1. Andreeva E.R., Mihailova I.A., Pygach I.M., Orehov A.N. 1999. Kletochnii sostav ateroskleroticheskih porajenii aorti cheloveka. Angiol. Sosyd. Hir. 5: 6-26.


2. Andreeva E.R., Tertov V.V., Myhin D.N., Orehov A.N. 1985. Kletochnii sostav i biohimicheskie osobennosti aorti cheloveka. Bull. VKNC AMN SSSR. 8: 63-71.


3. Ackermann R.T., Mulrow C.D., Ramirez G. et al. 2001. Garlic shows promise for improving some cardiovascular risk factors. Arch. Intern. Med. 161: 813-824.


4. Adams D.O. 1979. Macrophages. Methods Enzymol. 58: 494-505.


5. Edelson P.J., Kohn Z.A. 1976. Purification and Cultivation of Monocytes and Macrophages.In: In vitro methods in cell-mediated and tumor Immunity. Bloom B.R., David J.R., eds. Academic Press, Inc., New York. 333-340.


6. Hara A., Radin N.S. 1978. Lipid extraction of tissues with a low-toxicity solvent. Anal. Biochem. 90: 420-426.


7. Hernández R.H., Armas-Hernández M.J., Velasco M. et al. 2003. Calcium antagonists and atherosclerosis protection in hypertension. Am. J. Ther. 10: 409-414.


8. Loaldi A., Polese A., Montorsi P. et al. 1989. Comparison of nifedipine, propranolol and isosorbide dinitrate on angiographic progression and regression of coronary arterial narrowings in angina pectoris. Am. J. Cardiol. 64: 433-439.


9. Lowry O.H., Rosebrough N.J., Farr A.L., Randall B.J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.


10. Orekhov A.N., Andreeva E.R., Krushinsky A.V., Smirnov V.N. 1984. Primary cultures of enzyme-isolated cells from normal and atherosclerotic human aorta. Med. Biol. 62: 255-259.


11. Orekhov A.N., Karpova I.I., Tertov V.V. et al. 1984. Cellular composition of atherosclerotic and uninvolved human aortic subendothelial intima. Light-microscopic study of dissociated aortic cells. Am. J. Pathol. 115: 17-24.


12. Orekhov A.N., Tertov V.V., Novikov I.D. et al. 1985. Lipids in cells of atherosclerotic and uninvolved human aorta. I. Lipid composition of aortic tissue and enzyme-isolated and cultured cells. Exp. Mol. Pathol. 42: 117-137.


13. Orekhov A.N., Tertov V.V., Smirnov V.N. 1985. Lipids in cells of atherosclerotic and uninvolved human aorta. II. Lipid metabolism in primary culture. Exp. Mol. Pathol. 43: 187-195.


14. Peterkofsky B., Diegelmann R. 1971. Use of mixture of proteinase free collagenases for specific assay of radioactive collagen in the presence of other protiens. Biochemistry. 10: 988- 984.


15. Stary H.C. 1992. Composition and classification of human atherosclerotic lesions.Virchows. Arch. (A). 421: 277-290.


16. Stary H.C., Chandler A.B., Glagov S., et al. 1994. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation. 89: 2462-2478.


17. Stary H.C. 2000. Natural History and Histological Classification of Atherosclerotic Lesions: An Update. Arterioscler. Thromb. Vasc. Biol. 20: 1177-1178.


18. Tertov V.V., Orekhov A.N., Ryong L.H., Smirnov V.N. 1988. Intracellular cholesterol accumulation is accompanied by enhanced proliferative activity of human aortic intimal cells. Tissue. Cell. 20: 849-854.


19. Virella G., Mudoz J.F., Galbraith G.M.P. et al. 1995. Activation of human monocyte-derived macrophages by immune complexes containing low-density lipoprotein. Clin. Immunol. Immunopathol. 75: 179-189.



Свидетельство о регистрации сетевого электронного научного издания N 077 от 29.11.2006
Журнал основан 16 ноября 2000г.
Выдано Министерством РФ по делам печати, телерадиовещания и средств массовых коммуникаций
(c) Перепечатка материалов сайта Medline.Ru возможна только с письменного разрешения редакции

Размещение рекламы

Rambler's Top100