информационный портал
для специалистов

Физико-химическая биология

Клиническая медицина

Профилактическая медицина

Медико-биологические науки


Фундаментальные исследования

Организация здравохраниения

История медицины и биологии

Последние публикации

Поиск публикаций


Архив :  2000 г.  2001 г.  2002 г. 
               2003 г.  2004 г.  2005 г. 
               2006 г.  2007 г.  2008 г. 
               2009 г.  2010 г.  2011 г. 
               2012 г.  2013 г.  2014 г. 
               2015 г.  2016 г.  2017 г. 
               2018 г.  2019 г.  2020 г.  2021 г.  2022 г.  2023 г. 

Редакционная информация:
        Опубликовать статью
        Наша статистика

Главный редактор

Заместители главного редактора

Члены редколлегии
Специализированные редколлегии

Институт теоретической и экспериментальной биофизики Российской академии наук.


Адрес редакции и реквизиты

199406, Санкт-Петербург, ул.Гаванская, д. 49, корп.2

ISSN 1999-6314

Российская поисковая система

Vol. 12, Art. 49 (pp. 588-597)    |    2011       

Catheter associated infection in malignant lymphomas patients
A.K. Yurkin, A.V. Novitskiy, V.V. Tyrenko, A.V. Schegolev, D.A. Gornostayev

Military Medical Academy n.a. S.M. Kirov, Saint-Petersburg

Brief summary

Central vens catheterization is standard and effective transfusion providing method in hematological practice. But using central catheterization techniques lead to arising frequency of nosocomial blood infections in hematological patients especially with critical neutropenia. In this study a 57 cases of central veins cathetering were analyzed in malignant lymphomas patients. The frequency of catheter associated blood infections in this patients was studed and the most tupical germ distribution among studied patients was discovered. The new approaches to blood infections prophylaxis and treatment were suggested.

Key words

Catheterization, blood infection, hemoblastoses, malignant lymphomas, Hodgkin lymphomas, non-Hodgkin lymphomas.

(The article in PDF format. For preview need Adobe Acrobat Reader)

Open article in new window

Reference list

1. Mermel L. et al. Guidelines for the management of intravascular catheter-related infections // Clin. Infect. Dis.- 2001.- Vol. 32.- P. 1249–1272.

2. Warren D. et al. Nosocomial primary bloodstream infections in intensive care unit patients in a nonteaching community medical center: a 21-month prospective study // Clin. Infect. Dis. - 2001.- Vol. 33.- P. 1329–3135.

3. Bouza E. et al. A European perspective on intravascular catheter-related infections: report on the microbiology, workload, aetiology and antimicrobial susceptibility (ESGNI-005 Study) // Clin. Microbiol. Infect.- 2004.- Vol.10- P. 838–842.

4. McGee D. et al. Preventing complications of central venous catheterization. // N. Engl. J. Med.- 2003.- Vol.348.- P.1123–3113.

5. Munoz P. et al. Clinical-epidemiological characteristics and outcome of patients with catheter-related bloodstream infections in Europe (ESGNI-006 Study) // Clin. Microbiol. Infect .-2004.-Vol.10.-P. 843– 845.

6. Miller D. et al. Guidelines for the prevention of intravascular catheter-related infections: recommendations relevant to interventional radiology // J. Vasc. Intervent. Rad.-2003.- Vol.14.- P.133– 136.

7. Renaud B. et al. Outcomes of primary and catheter-related bacteremia //Am. J. Resp. Crit. Care Med.- 2001.- Vol.163.-P.1584–1590.

8. Walsh T. et al. All catheter-related candidemia is not the same: assessment of the balance between the risks and benefits of removal of vascular catheters // Clin. Infect. Dis.- 2002.- Vol.34.-P. 600–602.

9. Lee H. et al. Capacity of multidrug-resistant clinical isolates of Acinetobacter baumannii to form biofilm and adhere to epithelial cell surfaces // Microbiol. Infect.-2008.-Vol. 4.- P. 49–54.

10. Lai C. et al. Central venous catheter-related Stenotrophomonas maltophilia bacteraemia and associated relapsing bacteraemia in haematology and oncology patients // Microbiol. Infect.- 2006.- Vol.- 12.- P. 986–991.

11. Beukinga I. et al. Management of long-term catheter-related Brevibacterium bacteraemia // Clin. Microbiol. Infect.- 2004.- Vol.10.- P.465–467.

12. Safdar N. et al. The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters // Inten. Care Med.- 2004.- Vol.30.- P 62–67.

13. Blot F. et al. Diagnosis of catheter-related infections // Catheter-related infections. 2nd ed. New York, Marcel Dekker.- 2004.- P. 37–72.

14. Gilbert D. et al. Outpatient parenteral antimicrobial drug therapy // N. Engl. J. Med.- 1997.- Vol.337.-P. 829–838.

15. Sheretz RJ. et al. Pathogenesis of vascular catheter-related infections // eds. Catheter-related infections. New York. Marcel Dekker.- 1997-P. 1–30.

16. Pascual A. et al. Pathogenesis of catheter-related infections //. Clin. Microbiol. Infect .-2002.-Vol. 8.- P. 256–264.

17. O’Grady N. et al. Gudelines for the prevention of intravascular catheter-related infections // Infect. Dis.- 2002.- Vol.35.- P. 1281–1307.

18. Conlon R. et al. icaR incodes a transcriptional repressor involved in envirronmental regulation of ica operon expression and biofilm formation in Staphylococcus epidermidis // J. Bacterio.- 2002.-Vol.184.- P. 4400–4408.

19. Fitzpatrick F. et al. The genetics of staphylococcal biofilm formation – will a greater understanding of pathogenesis lead to better management of device-related infection // Clin. Microbiol. Infect.- 2005.- Vol.11.- P. 967–973.

20. Frebourg N. et al. PCR-Based assay for discrimination between invasive and contaminating Staphylococcus epidermidis strains // J. Clin. Microbiol.-2000.- Vol.38.- P. 877–880.

21. Rupp M. et al. Characterization of Staphylococcus epidermidis polysaccharide intercellular adhesion/hemagglutinin in the pathogenesis of intravascular catheter-associated infection in a rat // Infect. Immun.- 1999.- Vol.67.- P. 2656–2659.

22. Lyte M. et al. Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes // Lancet.- 2003.- Vol.361.- P. 130–135.

23. Maki D. et al. Pathogenesis, prevention and management of infections due to intravascular devices used for infusion therapy. In: Bisno A., Waldvogel F. eds. Infections associated with indwelling medical devices, 2nd ed. Washington D.C. // American Society for Microbiology.-1994.- P.155–212.

24. Safdar N. et al. Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection // Ann. Intern. Med.- 2005.- Vol.142.- P.451–466.

25. Franclin J. et al. In situ diagnosis of central venous catheter-related bloodstreem infection without peripheral blood culture // Pediatr. Infect. Dis. J.- 2004.-Vol.23.- P. 614–618.

26. Raad I. et al. Differential time to positivity: a useful method for diagnosing catheter-related bloodstream infections //Ann. Intern. Med.- 2004.- Vol.140- P. 18–25.

27. Jernigan J. et al. Short-course therapy of catheter-related Staphylococcus aureus bacteremia: a metaanalysis // Ann. Intern. Med.- 1993.- Vol.119.- P.304–311.

28. Lecciones J. et al. Vascular catheter-associated fungemia in patients with cancer: analysis of 155 episodes // Clin. Infect. Dis.- 1992.-Vol.14.- P. 875–883.

29. Raad I. et al. Catheter-related infections caused by Mycobacterium fortuitum complex: 15 cases and review // Infect. Dis.- 1991.-Vol.13.- P. 1120–1125.

30. Cunha A. et al. Methicillin-resistant Staphylococcus aureus: clinical manifestations and antimicrobial therapy // Clin. Microbiol. Infect.- 2005.- Vol.11.- Suppl. 4.- P. 33–42.

31. Simon A. et al. Diagnosis and treatment of catheter-related infections in pediatric oncology: an update // Clin. Microbiol. Infect.- 2006.- Vol.12- P. 606–620.

32. Isiklar Z. et al. Efficacy of antibiotics alone for orthopedic device related infections // Clin. Orthop.- 1996.- Vol.332.-P. 184–189.

33. Pascual,A. et al. Activity of glycopeptides in combination with amicacin or rifampicin against S.epidermidis biofilms on plastic catheters // Eur. J. Clin. Microb. Infect. Dis.- 1994.-Vol.13.- P. 515– 517.

34. Seifert H. et al. Central-venous catheters. Catheter-related infections. 2nd ed.// New York: Marcel Dekker.- 2004. P. 293–315.

35. Berrington A. et al. Use of antibiotic kocks to treat colonized central venous catheters // J. Antimicrob. Chemother.- 2001.-Vol.48.- P. 597–603.

36. Droste J. et al. Stability and in vitro efficacy of antibiotic-heperin lock solutions potentially useful for treatment of central venous catheter-related sepsis // J. Antimicrob. Chemother.- 2003.- Vol.51.- P. 849–855.

37. Poole C. et al. Treatment of catheter-related bacteraemia with an antibiotic lock protocol: effect of bacterial pathogen // Nephrol. Dial. Transplant. 2004.- Vol.19.- P.1237–1244.

38. Vencel P. Rykovodstvo po infekcionnomy kontrolu v stacionare. / Pod red. R.Vencel, T.Brever, J.Bytcler. // Per. s angl. Smolensk: MAKMAH. -2003.- S. 18–20.

39. Zybkov M. Consilium Medicum Hiryrgiya // M.N.Zybkov FGY Klinicheskaya bolnica Ypravleniya delami Prezidenta RF, Moskva.- №1.- 2008.- S.18-22.

40.Simon A. et al. Taurolidine-citrat lock solucion( TurLock) significantli reduces CVAD-associated grampositive infections pediatric cancer patients BMC // Diseases.- 2008.- P.102-109

41.Betjes M. Prevention of dialisis catheterrelated sepsis with a citrate-taurolidine-containing lock solution // Nephrol. Dial. Tansplant.- 2004.- Vol.19.- № 6.- P.1546-1551

Свидетельство о регистрации сетевого электронного научного издания N 077 от 29.11.2006
Журнал основан 16 ноября 2000г.
Выдано Министерством РФ по делам печати, телерадиовещания и средств массовых коммуникаций
(c) Перепечатка материалов сайта Medline.Ru возможна только с письменного разрешения редакции

Размещение рекламы

Rambler's Top100