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Федеральное государственное бюджетное учреждение науки
"Институт токсикологии Федерального медико-биологического агентства"
(ФГБУН ИТ ФМБА России)

Институт теоретической и экспериментальной биофизики Российской академии наук.

ООО "ИЦ КОМКОН".




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199406, Санкт-Петербург, ул.Гаванская, д. 49, корп.2

ISSN 1999-6314

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«
Vol. 12, Art. 16 (pp. 185-201)    |    feb 2011       

№ гос. регистрации: 0421100002\0016
»

Complex treatment of peritoneal cfrcinomatosis from colorectal cancer
Belayev A.M., Zakharenko A.A., Kondratsov S.A., Surov D.A., Babkov O.V.

Emergency Clinic of Oncology
Research joint venture to them. II Janelidze



Brief summary

Until recently, peritoneal carcinomatosis from colorectal cancer was a universally fatal manifestation of this cancer. However, two innovations in treatment have improved outcome for these patients. The new surgical interventions are collectively referred to as cytoreductive operation with peritonectomy procedures. During these procedures, all visible cancer is removed in an attempt to leave the patient with only microscopic residual disease. Perioperative intraperitoneal chemotherapy, the second innovation, is employed to eradicate small-volume residual disease. The intraperitoneal chemotherapy is administered in the operating room with moderate hyperthermia and is referred to as heated intraoperative intraperitoneal chemotherapy. If tolerated, additional intraperitoneal chemotherapy can be administered during the first 5 postoperative days. The use of these combined treatments, cytoreductive surgery and intraperitoneal chemotherapy, improves survival, optimizes quality of life, and maximally preserves function. This article describes the natural history of intraperitoneal chemotherapy witn hyperthermia, and the benefits and limitations of intraperitoneal chemotherapy. Peritonectomy procedures are defined and described. Also presented are the mechanics of delivering perioperative intraperitoneal chemotherapy and the clinical assessments used to select patients who will benefit from combined treatment. The results of combined treatment for colorectal carcinomatosis are presented.


Key words

colorectal cancer, peritoneal carcinomatosis, intraperitoneal chemotherapy witn hyperthermia, рeritonectomy, cytoreductive operation.





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Reference list

1. Chissov V.I., Starinskii V.V. Sostoyanie onkologicheskoi pomoshi stran SNG. — M., 2000. - S. 48-51.


2. Jayne D.G., Fook S., Loi C. et al. Peritoneal carcinomatosis from colorectal cancer // Br. J. Surg. - 2002. - Vol.89. - P. 1545–1550.


3. Koppe M.J., Boerman O.C., Wim J.G. et al. Peritoneal Carcinomatosis of Colorectal Origin. Incidence and Current Treatment Strategies // Ann. Surg. - 2006. - Vol.243, №2. - P. 212-222.


4. Chu D.Z., Lang N.P., Thompson C. et al. // Peritoneal carcinomatosis in nongynecologic malignancy. A prospective study of prognostic factors // Cancer – 1989. - Vol.63. – P. 364-367.


5. Sadeghi B., Arvieux C., Glehen O. et al. Peritoneal carcinomatosis from non-gynecologic malignancies: results of the EVOCAPE 1 multicentric prospective study // Cancer – 2000. - Vol.88. - P. 358-363.


6. Sugarbaker P.H. Peritoneum as the first-line of defense in carcinomatosis // J. Surg. Oncol. - 2007. - Vol.95. - P. 93-96.


7. Spratt J.S., Adcock R.A., Sherrill W. et al. Hyperthermic peritoneal perfusion system in canines // Cancer Res. - 1980. - Vol.40. - P. 253–255.


8. Spratt J.S., Adcock R.A., Muskovin M. et al. Clinical delivery system for intraperitoneal hyperthermic chemotherapy // Cancer Res. - 1980. - Vol.40. - P. 256–260.


9. Sugarbaker P.H., Kern K., Lack E. Malignant pseudomyxoma peritonei of colonic origin: natural history and presentation of a curative approach to treatment // Dis. Colon Rectum - 1987. - Vol.30. - P. 772–779.


10. Sugarbaker P.H. Surgical management of peritoneal carcinosis: diagnosis, and treatment // Langenbecks Arch. Chir. - 1988. - Vol.373. - P. 189–196.


11. Sugarbaker P.H. Peritoneal carcinomatosis: natural history and rational therapeutic interventions using intraperitoneal chemotherapy // Cancer Treat. Res. - 1996. - Vol.81. - P. 149- 168.


12. Ceelen W.P., Hesse U., De Hemptinne B. et al. Hyperthermic intraperitoneal chemoperfusion in the treatment of locally advanced intra-abdominal cancer // Br. J. Surg. - 2000. - Vol.87. - P. 1006 –1015.


13. Jacquet P., Zhu B.W., Sugarbaker P.H. et al. Peritoneal carcinomatosis from intraabdominal malignancy: natural history and new prospects for management // Acta. Belg. Chir. - 1994. - Vol.94. - P. 191-197.


14. Osinskii D.S., Bejar A., Chernii V.A. i dr. Vnytribrushnaya himiogipertermicheskaya perfyziya i citoredyktivnaya operaciya v lechenii bolnih karcinomatozom brushnoi polosti // Onkologiya - 2003. - T.5, №1. - S. 55-62.


15. Sugarbaker P.H. Review of a personal experience in the management ofcarcinomatosis and sarcomatosis // Jpn. J. Clin. Oncol. - 2001. - Vol.31. - P. 573-583.


16. Elias D. La chirurgie de reduction tumorale: mythe ou re-alite? // J. Chir. - 1992. - Vol.129. - P. 479-483.


17. Rampone B., Schiavone B., Martino A. et al. Current role of hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from colorectal cancer // World J. Gastroenterol. - 2010. - Vol.16, №11. - P. 1299-1302.


18. Van der Speeten K., Stuart O.A., Sugarbaker P.H. Using pharmacologic data to plan clinical treatments for patients with peritoneal surface malignancy // Curr. Drug. Discov. Technol. - 2009. - Vol.6. - P. 72-81.


19. Elias D.M., Sideris L. Pharmacokinetics of heated intraoperative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis // Surg. Oncol. Clin. N. Am. - 2003. - Vol.12. - P. 755-769


20. Petrov V., Kitaev A. Citoredyktivnie operacii i vnytribrushnaya gipertermicheskaya himioterapiya pri lechenii bolnih s kolorektalnim rakom // Medicinskaya gazeta - 2005. - №80. - S. 3-6.


21. Fernandez-Trigo V., Stuart O.A., Stephens A.D. et al. Surgically directed chemotherapy: Heated intraperitoneal lavage with mitomycin C. In: Sugarbaker P.H. (ed.); Peritoneal Carcinomatosis: Drugs and Diseases // Kluwer: Boston – 1996. - P. 51-61.


22. Stephens A.D., Belliveau J., Sugarbaker P.H. Intraoperative hyperthermic lavage with cisplatin for peritoneal carcinomatosis and sarcomatosis. In: Sugarbaker P.H. (ed.); Peritoneal Carcinomatosis: Drugs and Diseases // Kluwer: Boston – 1996. - P. 15-30.


23. Sugarbaker P.H. Peritonectomy procedures // Ann. Surg. – 1995. – Vol.221. – P. 29-42.


24. Sugarbaker P.H. Review of a personal experience in the management ofcarcinomatosis and sarcomatosis // Jpn. J. Clin. Oncol. – 2001. – Vol.31. – P.573-83.


25. Sugarbaker P.H. Surgical Management of Carcinomatosis from Colorectal Cancer // Clinics in colon and rectal surg. – 2005. – Vol.18, №3. - R. 190-203.


26. Sugarbaker P.H. Patterns of failure following treatment of pseudomyxoma peritonei of appendiceal origin // Eur. J. Cancer – 1996. – Vol.32A, №10 – P. 1727-1733.


27. Glehen O., Peyrat A., Beaujard A.C. et al. Abdominal cancer with peritoneal carcinomatosis treated by peritonectomy procedure and intraperitoneal chemohyperthermia // Exp. Oncology – 2000. – Vol.22. – P. 59-63.


28. Glehen O., Mithieux F., Osinsky D. et al. Surgery combined with peritoneotomy procedures and intraperitoneal chemohyperthermia in abdominal cancers with peritoneal carcinomatosis: a phase II study // J. Clin. Oncol. – 2003. – Vol.21. – P. 799-806.


29. Jacquet P., Stephens A.D., Averbach A.M. et al. Analysis of morbidity and mortality in 60 patients with peritoneal carcinomatosis treated by cytoreductive surgery and heated intraoperative intraperitoneal chemotherapy // Cancer – 1996. – Vol.77. – P. 2622- 2629.


30. Schneebaum S., Arnold M.W., Staubus A. et al. Intraperitoneal hyperthermic perfusion with mitomycin S for colorectal cancer with peritoneal metastases // Ann. Surg. Oncol. – 1996. – Vol.3. – P. 44-50.


31. Loggie B.W., Fleming R.A., McQuellon R.P. et al. Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of gastrointestinal origin // Ann. Surg. – 2000. - Vol.66. – P. 561-568.


32. Witkamp A..J., de Bree E., Kaag M.M. et al. Extensive cytoreductive surgery followed by intraoperative hyperthermic intraperitoneal chemotherapy with mitomycin-C in patients with peritoneal carcinomatosis of colorectal cancer // Eur. J. Cancer – 2001. – Vol.37. – P. 979-984.


33. da Silva R.G., Sugarbaker P.H. Analysis of prognostic factors in seventy patients having a complete cytoreduction plus perioperative intraperitoneal chemotherapy for carcinomatosis from colorectal cancer // J. Am. Coll. Surg. – 2006. – Vol.203. – P. 878-886.


34. Verwaal V.J., van Ruth S., de Bree E. et al. Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer // J. Clin. Oncol. – 2003. – Vol.21. – P. 3737-3743.


35. Elias D., Blot F., Antoun S. et al. Curative treatment of peritoneal carcinomatosis arising from colorectal cancer by complete resection and intraperitoneal chemotherapy // Cancer – 2001. – Vol.92. – P. 71-76.


36. Glehen O., Cotte E., Schreiber V. et al. Intraperitoneal chemohyperthermia and attempted cytoreductive surgery in patients with peritoneal carcinomatosis of colorectal origin // Br. J. Surg. – 2004. – Vol.91. – P. 747-754.


37. Sugarbaker P.H., Verwaal V.J., van Tinteren H. et al. Toxicity of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy // J. Surg. Oncol. – 2004. – Vol.85. – P. 61-67.


38. Glehen O., Osinsky D., Cotte E. et al. Intraperitoneal chemohyperthermia using a closed abdominal procedure and cytoreductive surgery for the treatment of peritoneal carcinomatosis: morbidity and mortality analysis of 216 consecutive procedures // Ann. Surg. Oncol. – 2003. – Vol.10. – P. 863-869.


39. Stephens A.D., Alderman R., Chang D. et al. Morbidity and mortality analysis of 200 treatments with cytoreductive surgery and hyperthermic intraoperative intraperitoneal chemotherapy using the coliseum technique // Ann. Surg. Oncol. – 1999. – Vol.6. – P. 790-796.


40. Shen P., Hawksworth J., Lovato J. et al. Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy with mitomycin C for peritoneal carcinomatosis from nonappendiceal colorectal carcinoma // Ann. Surg. Oncol. – 2004. – Vol.11. – P. 178-186.


41. Verwaal V.J., van Ruth S., Witkamp A. et al. Long-term survival of peritoneal carcinomatosis of colorectal origin // Ann. Surg. Oncol. – 2005. – Vol.12. – P. 65-71.


42. Elias D., Benizri E., Pocard M. et al. Treatment of synchronous peritoneal carcinomatosis and liver metastases from colorectal cancer // Eur. J. Surg. Oncol. – 2006. – Vol.32 – P. 632-636.


43. Kianmanesh R., Scaringi S., Sabate J.M. et al. Iterative cytoreductive surgery associated with hyperthermic intraperitoneal chemotherapy for treatment of peritoneal carcinomatosis of colorectal origin with or without liver metastases // Ann. Surg. – 2007. – Vol.245. – P. 597-603.


44. Esquivel J., Sticca R., Sugarbaker P.H. et al. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of Surgical Oncology // Ann. Surg. Oncol. – 2007. – Vol.14. – P. 128-133.


45. Elias D., Goéré D., Di Pietrantonio D. et al. Results of systematic second-look surgery in patients at high risk of developing colorectal peritoneal carcinomatosis // Ann. Surg. – 2008. - Vol.247. – P. 445-450.


46. Brouquet A., Goéré D., Lefèvre J.H. et al. The second procedure combining complete cytoreductive surgery and intraperitoneal chemotherapy for isolated peritoneal recurrence: postoperative course and long-term outcome // Ann. Surg. Oncol. – 2009. – Vol.16. – P. 2744- 2751.


47. Mc Quellon R.P., Loggie B.W., Fleming R.A. et al. Quality of life after intraperitoneal hyperthermic chemotherapy (IPHC) for peritoneal carcinomatosis // Eur. J. Surg. Oncol. – 2001. – Vol.27. – P. 65–73.


48. Mc Quellon R.P., Loggie B.W., Lehman A.B. et al. Long-term survivorship and quality of life after cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis // Ann. Surg. Oncol. – 2003. – Vol.10. P. 155–162.



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