Опубликовать статью

Информационное партнерство

Инфоресурсы

Контакты

«

Vol. 11, Art. 43 (pp. 518-525)    |    2010       

№ гос. регистрации: 0421000002043

»

The pharmacological correction of hyperammoniemisis conditions at the criminal poisoning clozapine

D.G. Slyundin 1, A.V. Aleкhnovich 2, V.B. Ivanov 2, A.S. Livanov 1, V.V.Anuchin 1

1- City Hospital № 33 named. prof. AA Ostroumov Department of Health, Moscow (107014, Moscow, st. Strominka d.7)
2- National Institute of Advanced Medical Defense Ministry (109545, Moscow, st. MG Cherkizovskaya, 7)

Brief summary

Summary: 221 patients were investigated on endotoxicosis with the diagnosis of a criminal poisoning by clozapine. It is established that ammonia of plasma’s blood is the earliest and informative indicator of endotoxicosis, concentration by which increases with severity of a chemical trauma in 1,2-2,1 times (р<0,05). The treatment with hypoammoniemic drug amino acid - L-ornitin, L-aspartat («Hepa-Merz») is accompanied by authentic reducing of treatment terms for patients and normalizing of psycho physiological conditions in earlier terms.


Key words

hyperammoniemia, criminal poisoning, clozapine, ammiak, L-ornithinе, L-aspartate

Reference list