Опубликовать статью

Информационное партнерство

Инфоресурсы

Контакты

«

Vol. 11, Art. 39 (pp. 467-481)    |    2010       

№ гос. регистрации: 0421000002039

»

the using of different programs of hemotransfusion therapy in homozygous of beta-thalassaemia

D.A.Baytayeva, S.S. Bessmeltsev

Azerbaijan Institute of Scientific-Researching of Hematology and Transfusiology, Baku
Russian Research Institute of Hematology and Transfusiology

Brief summary

The article represents the results of different programs of hemotransfusion therapy in patients with homozygous forms of β-thalassemia. The selection of therapeutic program must be based on the analysis of hereditary pathology of blood system, the capacities of liver and the metabolism of ferroporphyrine complex. The usefulness of complex therapy which includes the transfusion of red blood cells components, the using of deferoxamine, hepatoprotectors and plasmapheresis was demonstrated. The therapy of anemia syndrome in these cases was easier and the therapeutic effect was more stable. The using of plasmapheresis leads to the depletion of side effects, omission of additional hemotransfusions and decrease of ferric overload.


Key words

homozygous β-thalassemia, protoporphirine, deferoxamine, plasmapheresis, red blood cells components

Reference list