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Vol. 11, Art. 27 (pp. 331-337)    |    2010       

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Influence irgastab PVC76 on detoxication liver function

Fomin M.V.

State Educational Organization of Higher Professional Education "Saint-Petersburg State Medical Academy after I.I. Mechnikov of the Federal Agency for Public Health and Social Development of the Russian Federation"

Brief summary

The article presents the materials of toxicological studies of a new component of the production of polyvinylchloride, an antioxidant IRGASTAB PVC76, on the detoxifying function of the liver. Shown that the test substance inhibits the activity of enzymes of the endoplasmic reticulum of hepatocytes, which could lead to a breach of the detoxifying liver function.


Key words

enzymes, the endoplasmic reticulum of hepatocytes

Reference list

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